Ethanol affects calmodulin and the calmodulin-binding proteins neuronal nitric oxide synthase and alphaII-spectrin (alpha-fodrin) in the nucleus of growing and differentiated rat astrocytes in primary culture.

@article{Toms2007EthanolAC,
  title={Ethanol affects calmodulin and the calmodulin-binding proteins neuronal nitric oxide synthase and alphaII-spectrin (alpha-fodrin) in the nucleus of growing and differentiated rat astrocytes in primary culture.},
  author={M{\'o}nica Tom{\'a}s and Mar{\'i}a Pilar Mar{\'i}n and Manuel Portol{\'e}s and Lu{\'i}s Meg{\'i}as and M. Jos{\'e} G{\'o}mez-lech{\'o}n and Jaime Renau-Piqueras},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2007},
  volume={21 6},
  pages={1039-49}
}
The distribution of calmodulin (CaM) and the CaM-binding proteins neuronal nitric oxide synthase (nNOS) and alphaII-spectrin (alpha-fodrin) in the nucleus of growing and differentiated astrocytes was analysed using immunogold electronmicroscopy. We also analysed the effect of moderate ethanol exposure on these proteins. For this, female Wistar rat were fed with an alcoholic liquid diet and exposed to males after several weeks. Pregnant rats were fed with this diet and, after birth, the foetuses… CONTINUE READING