Ethanol, wine, and experimental cardioprotection in ischemia/reperfusion: role of the prooxidant/antioxidant balance.

@article{Rakotovao2004EthanolWA,
  title={Ethanol, wine, and experimental cardioprotection in ischemia/reperfusion: role of the prooxidant/antioxidant balance.},
  author={Andry Rakotovao and Corinne Berthonneche and Annabelle Guiraud and Michel de Lorgeril and Patricia Salen and Jo{\"e}l de Leiris and Francois R. Boucher},
  journal={Antioxidants & redox signaling},
  year={2004},
  volume={6 2},
  pages={431-8}
}
It is now well established that oxidative stress resulting from reactive oxygen species (ROS) that are generated in cardiac myocytes subjected to ischemia/reperfusion plays a causative role in the development of heart failure and may contribute to promote cell death. During the last decade, several groups have reported that, in animal models of myocardial ischemia/reperfusion, certain nutrients, including ethanol and nonethanolic components of wine, may have a specific protective effect on the… CONTINUE READING