Etanercept treatment enhances clinical and neuroelectrophysiological recovery in partial spinal cord injury

@article{Bayrakli2012EtanerceptTE,
  title={Etanercept treatment enhances clinical and neuroelectrophysiological recovery in partial spinal cord injury},
  author={Fatih Bayrakli and H Yasemin Balaban and Unal Ozum and Cevdet Duger and Suat Ahmet Topaktas and Hamit Zafer Kars},
  journal={European Spine Journal},
  year={2012},
  volume={21},
  pages={2588-2593}
}
To investigate the effect of an anti-TNF-α agent (etanercept) on recovery processes in a partial spinal cord injury (SCI) model using clinical and electrophysiological tests. Twenty-four New Zealand rabbits were divided into three groups: group 1 [SCI + 2 ml saline intramuscular (i.m.), n = 8], group 2 (SCI + 2.5 mg/kg etanercept, i.m., 2–4 h after SCI, n = 8) and group 3 (SCI + 2.5 mg/kg etanercept, i.m., 12–24 h after SCI, n = 8). Rabbits were evaluated before SCI, immediately after SCI, 1… CONTINUE READING

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