Etanercept administration prevents the inflammatory response induced by carrageenan in the murine air pouch model

@article{Mattei2015EtanerceptAP,
  title={Etanercept administration prevents the inflammatory response induced by carrageenan in the murine air pouch model},
  author={Rodrigo Ant{\^o}nio Mattei and Eduardo Monguilhott Dalmarco and T{\^a}nia Silvia Fr{\"o}de},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2015},
  volume={388},
  pages={1247-1257}
}
Rheumatoid arthritis (RA) is one of several inflammatory and autoimmune diseases that affect approximately 1 % of world’s population. The development of TNF inhibitors in the last decade represents a great advance in the treatment of mild and severe forms of RA. Etanercept is one of these drugs that is useful for RA treatment, but the mechanism of inhibition of the signaling pathway of inflammation was not completely elucidated. This study was conducted to evaluate the anti-inflammatory effect… CONTINUE READING
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