Estrogens in insects

@article{Mechoulam2005EstrogensII,
  title={Estrogens in insects},
  author={Raphael Mechoulam and Robert W. Brueggemeier and Danielle Denlinger},
  journal={Experientia},
  year={2005},
  volume={40},
  pages={942-944}
}
Insects representing 5 different orders contain androgen and estrogen-like substances as determined by radioimmunoassay. Estradiol and estriol have been identified by gas chromatography-mass spectrometry. The presence of these steroids in insects suggests that the vertebrate sex hormones have an ancient evolutionary history. 
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