Estrogens and selective estrogen receptor modulators in acromegaly
@article{Duarte2016EstrogensAS, title={Estrogens and selective estrogen receptor modulators in acromegaly}, author={Felipe H. G. Duarte and Raquel Soares Jallad and Marcello Delano Bronstein}, journal={Endocrine}, year={2016}, volume={54}, pages={306-314} }
Despite recent advances in acromegaly treatment by surgery, drugs, and radiotherapy, hormonal control is still not achieved by some patients. The impairment of IGF-1 generation by estrogens in growth hormone deficient patients is well known. Patients on oral estrogens need higher growth hormone doses in order to achieve normal IGF-1 values. In the past, estrogens were one of the first drugs used to treat acromegaly. Nevertheless, due to the high doses used and the obvious side effects in male…
12 Citations
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