Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues

@article{Somjen2004EstrogenicAO,
  title={Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues},
  author={D. Somjen and S. Katzburg and J. Vaya and A. Kaye and S. Tamir},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={2004},
  volume={91},
  pages={241-246}
}
  • D. Somjen, S. Katzburg, +2 authors S. Tamir
  • Published 2004
  • Chemistry, Medicine
  • The Journal of Steroid Biochemistry and Molecular Biology
  • Data from both in vivo and in vitro experiments demonstrated that glabridin and glabrene are similar to estradiol-17beta in their stimulation of the specific activity of creatine kinase, although at higher concentrations, but differ in their extent of action and interaction with other drugs. In pre-menopausal human bone cells, the response to estradiol-17beta and glabridin (at higher concentration) was higher than in post-menopausal cells; whereas, glabrene (at higher concentration) was more… CONTINUE READING
    50 Citations
    Estrogenicity of Glabridin in Ishikawa Cells
    • 11
    • PDF
    Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra)
    • 38
    • PDF
    Absorption of dietary licorice isoflavan glabridin to blood circulation in rats.
    • 31
    • PDF
    Estrogenic activities of extracts of Chinese licorice (Glycyrrhiza uralensis) root in MCF-7 breast cancer cells
    • 37
    • PDF
    Phytochemistry and biological properties of glabridin.
    • 102

    References

    SHOWING 1-10 OF 35 REFERENCES
    Estrogen-like activity of licorice root constituents: glabridin and glabrene, in vascular tissues in vitro and in vivo
    • 74
    • PDF
    Estrogen-like activity of glabrene and other constituents isolated from licorice root
    • 203
    Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells.
    • 173
    • PDF
    Effects of phytoestrogens on DNA synthesis and creatine kinase activity in vascular cells.
    • 34
    • PDF
    Reciprocal modulation by sex steroid and calciotrophic hormones of skeletal cell proliferation
    • 26