Estrogenic activity and reproductive effects of the UV-filter oxybenzone (2-hydroxy-4-methoxyphenyl-methanone) in fish.

@article{Coronado2008EstrogenicAA,
  title={Estrogenic activity and reproductive effects of the UV-filter oxybenzone (2-hydroxy-4-methoxyphenyl-methanone) in fish.},
  author={Michael Coronado and Hector De Haro and Xin Deng and M. A. Rempel and Ram{\'o}n Lavado and Daniel Schlenk},
  journal={Aquatic toxicology},
  year={2008},
  volume={90 3},
  pages={182-7}
}
Previous studies in extracts of sediments surrounding municipal outfalls off the coast of California, USA and effluents of New York City, NY, USA indicated the UV-filtering agent, oxybenzone (CAS# 131-57-7; benzophenone-3) as a potential estrogen. The effects of oxybenzone on estrogenic activity and reproduction were evaluated using a 14-day juvenile rainbow trout assay for plasma vitellogenin and a subsequent 21-day Japanese medaka reproduction assay. Significant induction of vitellogenin was… CONTINUE READING
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