Estrogenic activities of chemicals in diesel exhaust particles.

@article{Mori2002EstrogenicAO,
  title={Estrogenic activities of chemicals in diesel exhaust particles.},
  author={Y. Mori and S. Taneda and H. Hayashi and A. Sakushima and K. Kamata and A. Suzuki and S. Yoshino and M. Sakata and M. Sagai and K. Seki},
  journal={Biological \& pharmaceutical bulletin},
  year={2002},
  volume={25 1},
  pages={
          145-6
        }
}
In a previous study, we focused on estrogenic activity of the hexane extract of diesel exhaust particles (DEP). The extract of hexane was first fractionated to acidic, phenolic and neutral portions according to their chemical properties, of which the neutral fraction was fractionated by column chromatography on silica gel. The chemical structures of compounds in these fractions were then analyzed. It was found that the neutral fraction of the hexane extract of DEP contains dibenzothiophene… Expand
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TLDR
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Both type-1 and type-2 DEP possess estrogenic and anti-estrogenic activities, and extracts of both types decreased the activity of estrogen. Expand
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It is thought that those compounds in DEP can modulate the activity of estrogen, leading to the distruption of balance between estrogen and androgen. Expand
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Abstract The polynuclear aromatic compound fractions (PAC) separated by column chromatography from five diesel fuels, a gas oil and sample of kerosene were analysed by capillary column gasExpand
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An estrogen-inducible screen was developed in yeast (Saccharomyces cerevisiae) in order to assess whether surfactants and their major degradation products are estrogenic. The DNA sequence of theExpand
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Findings from in vitro and in vivo studies which confirm that a range of alkyl hydroxy benzoate preservatives (parabens) are weakly estrogenic are reported, suggesting that the safety in use of these chemicals should be reassessed. Expand
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TLDR
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TLDR
The 3-Hydroxyl and 17beta-hydroxyl groups of 17 beta-E(2) are not absolute requirements for estrogenicity, and the crystal structure of the bisdesoxy- E(2)/ER complex to be evaluated is evaluated. Expand
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Abstract The organosulfur compounds present in fossil fuels vary widely in their reactivities in catalytic hydrodesulfurization. In naphtha, thiophene is so much less reactive than the thiols,Expand
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