Estrogen-triggered delays in mammary gland gene expression during the estrous cycle: evidence for a novel timing system.

@article{Silberstein2006EstrogentriggeredDI,
  title={Estrogen-triggered delays in mammary gland gene expression during the estrous cycle: evidence for a novel timing system.},
  author={Gary B. Silberstein and Katharine Van Horn and Eva Hrabeta-Robinson and Jennifer E Compton},
  journal={The Journal of endocrinology},
  year={2006},
  volume={190 2},
  pages={225-39}
}
During the estrous cycle and beginning in estrus, the mammary gland undergoes pregnancy-like development that depends on transcriptional regulation by the estrogen and progesterone receptors (ER, PR) and Pax-2 as well as the action of the growth factors Wnt-4 and RANKL. In this report, we first describe the decay and delayed expression of ERalpha, PR, and Pax-2 proteins as well as depression of Wnt-4 and RANKL mRNA coincident with the strong estrogen surge in proestrus. In time-course studies… CONTINUE READING

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During the estrous cycle and beginning in estrus , the mammary gland undergoes pregnancy - like development that depends on transcriptional regulation by the estrogen and progesterone receptors ( ER , PR ) and Pax-2 as well as the action of the growth factors Wnt-4 and RANKL .
During the estrous cycle and beginning in estrus , the mammary gland undergoes pregnancy - like development that depends on transcriptional regulation by the estrogen and progesterone receptors ( ER , PR ) and Pax-2 as well as the action of the growth factors Wnt-4 and RANKL .
During the estrous cycle and beginning in estrus , the mammary gland undergoes pregnancy - like development that depends on transcriptional regulation by the estrogen and progesterone receptors ( ER , PR ) and Pax-2 as well as the action of the growth factors Wnt-4 and RANKL .
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