Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils.

@article{GarcaDurn1999EstrogenSN,
  title={Estrogen stimulates neuronal nitric oxide synthase protein expression in human neutrophils.},
  author={Margarita Garc{\'i}a-Dur{\'a}n and Trinidad de Frutos and Joaqu{\'i}n D{\'i}az-Recasens and G Garc{\'i}a-G{\'a}lvez and Amparo Jim{\'e}nez and Mercedes Mont{\'o}n and J{\'e}ronimo Farr{\'e} and Lourdes S{\'a}nchez de Miguel and Fernando Gonz{\'a}lez-Fern{\'a}ndez and Mar{\'i}a del Mar Arriero and Luis A Rico and Ra{\'u}l Ignacio Ramos Garc{\'i}a and S. Pulido Casado and Antonio L{\'o}pez-Farr{\'e}},
  journal={Circulation research},
  year={1999},
  volume={85 11},
  pages={1020-6}
}
Recent studies have postulated the contribution of nitric oxide (NO) released by the endothelium to the beneficial effects of estrogen. Despite a neuronal-type NO synthase (nNOS) described in neutrophils, less is known about the effect of estrogen in these cells. The aim of the present study was to analyze the expression of nNOS protein in human neutrophils under different estrogenic conditions. We first analyzed nNOS expression in neutrophils obtained from premenopausal women. During the first… CONTINUE READING