Estrogen reverses nicotine-induced inflammation in chondrocytes via reducing the degradation of ECM.

@article{Peng2019EstrogenRN,
  title={Estrogen reverses nicotine-induced inflammation in chondrocytes via reducing the degradation of ECM.},
  author={Xiaoyun Peng and Zhiguang Qiao and You Wang and Huiqin Li and Yilin Xie and Mei Xin and Zhongdong Qiao and Zhaoxia Wang},
  journal={International journal of rheumatic diseases},
  year={2019}
}
PROBLEM Osteoarthritis (OA) is a chronic disease with a very high incidence and the pathology of which is quite complex. Epidemiological investigation showed that OA may be related to smoking and estrogen levels, but there are few studies focused on the cross-effect of these two factors. This research aims to investigate the molecular mechanism of nicotine and estrogen effects on chondrocytes to study the effect of smoking on the incidence of osteoarthritis in women. METHOD OF THE STUDY… CONTINUE READING
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