Estrogen replacement improves skeletal muscle performance by increasing parvalbumin levels in ovariectomized rats.

@article{Bunratsami2015EstrogenRI,
  title={Estrogen replacement improves skeletal muscle performance by increasing parvalbumin levels in ovariectomized rats.},
  author={Suchirat Bunratsami and Wandee Udomuksorn and Ekkasit Kumarnsit and Surapong Vongvatcharanon and Uraporn Vongvatcharanon},
  journal={Acta histochemica},
  year={2015},
  volume={117 2},
  pages={163-75}
}
Muscle weakness is common during menopause. Effective estrogen replacement was hypothesized to prevent sarcopenia. This study aimed to investigate the estrogen level, estrogen receptors (α and β) immunoreactivities, muscle mass and functions, and parvalbumin (PV) levels in the extensor digitorum longus (EDL) and the gastrocnemius muscles of ovariectomized rats. Adult female Wistar rats (12 weeks old) were divided into five groups: sham-operated (SHAM), and ovariectomized (E0) groups that… CONTINUE READING