Estrogen receptors and estrogen sensitivity of fetal thymocytes are restricted to blast lymphoid cells.

@article{Gulino1985EstrogenRA,
  title={Estrogen receptors and estrogen sensitivity of fetal thymocytes are restricted to blast lymphoid cells.},
  author={Alberto Gulino and Isabella Screpanti and Maria Rosaria Torrisi and Luigi Frati},
  journal={Endocrinology},
  year={1985},
  volume={117 1},
  pages={47-54}
}
We have observed [3H]estradiol binding sites in the cytosol of lymphoid cell suspensions obtained from the fetal thymus of guinea pig. Scatchard analysis [dissociation constant (Kd), 0.5 +/- 0.02 (SE) nM], binding specificity, and diethylaminoethyl chromatography of these [3H]estradiol binding sites are similar to those described for estrogen receptors. Estrogen receptor levels in the thymic lymphoid cell population have been studied after fractionating cells by Percoll discontinuous density… CONTINUE READING
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