Estrogen receptor function as revealed by knockout studies: neuroendocrine and behavioral aspects.

@article{Rissman1997EstrogenRF,
  title={Estrogen receptor function as revealed by knockout studies: neuroendocrine and behavioral aspects.},
  author={Emilie F. Rissman and Scott R. Wersinger and J. Andrew Taylor and Dennis B. Lubahn},
  journal={Hormones and behavior},
  year={1997},
  volume={31 3},
  pages={232-43}
}
Estrogens are an important class of steroid hormones, involved in the development of brain, skeletal, and soft tissues. These hormones influence adult behaviors, endocrine state, and a host of other physiological functions. Given the recent cloning of a second estrogen receptor (ER) cDNA (the ER beta), work on alternate spliced forms of ER alpha, and the potential for membrane estrogen receptors, an animal with a null background for ER alpha function is invaluable for distinguishing biological… CONTINUE READING

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