Estrogen receptor expression in the genital tract of female mice treated neonatally with diethylstilbestrol.

@article{Sato1992EstrogenRE,
  title={Estrogen receptor expression in the genital tract of female mice treated neonatally with diethylstilbestrol.},
  author={Tomoyuki Sato and Hitoshi Okamura and Yasuhiko Ohta and Shinichi Hayashi and Yuzo Takamatsu and Noboru Takasugi and Taisen Iguchi},
  journal={In vivo},
  year={1992},
  volume={6 2},
  pages={
          151-6
        }
}
The distribution of the estrogen receptor (ER) was investigated immunohistochemically in the genital tract of 0 (day of birth)--to 50-day-old C57BL/Tw female mice given 5 daily injections of 2 micrograms diethylstilbestrol (DES) from the day of birth using an anti-ER monoclonal antibody. In the oviduct, cervix and vagina of control mice, both epithelial and stromal cell nuclei showed positive ER immunoreaction at 0 day. Nuclei of uterine stromal cells also showed strong ER immunostaining even… CONTINUE READING

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