Estrogen receptor-beta is expressed in Barrett's metaplasia and associated adenocarcinoma of the esophagus.

@article{Akgun2002EstrogenRI,
  title={Estrogen receptor-beta is expressed in Barrett's metaplasia and associated adenocarcinoma of the esophagus.},
  author={Hulya Akgun and Juan Lechago and Mamoun Younes},
  journal={Anticancer research},
  year={2002},
  volume={22 3},
  pages={1459-61}
}
Estrogen receptor-beta (ER-B) has been identified in benign and malignant tissues of a variety of human organs including the colon. In breast carcinoma, ER-B was found to be a significant predictor of response to adjuvant hormonal therapy with tamoxifen. The aim of the present study was to determine whether esophageal adenocarcinoma, and its precursosr, Barrett's metaplasia, express ER-B. Sections of formalin-fixed and paraffin-embedded tissue from 31 esophagectomy specimens were immunostained… CONTINUE READING
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