Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice.

@article{Nomura2006EstrogenRG,
  title={Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice.},
  author={Masayoshi Nomura and Sandra E C Andersson and KennethS. Korach and Jan-{\AA}ke Gustafsson and Donald W. Pfaff and Sonoko Ogawa},
  journal={The European journal of neuroscience},
  year={2006},
  volume={23 7},
  pages={
          1860-8
        }
}
Aggressive behaviour of gonadally intact male mice is increased by estrogen receptor (ER)-beta gene disruption, whereas sexual behaviour remains unchanged. The elevated aggression levels following ER-beta gene disruption is pronounced during repeated aggression tests in young animals and the first aggression test in adults. In the present study, the roles of ER-beta activation in the regulation of aggressive and sexual behaviour were investigated in gonadectomized ER-beta knockout (betaERKO… CONTINUE READING
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