Estrogen receptor beta (ERbeta) mRNA and protein in serotonin neurons of macaques.

  title={Estrogen receptor beta (ERbeta) mRNA and protein in serotonin neurons of macaques.},
  author={Chrisana Gundlah and Nick Z Lu and Stephanie J Mirkes and Cynthia L Bethea},
  journal={Brain research. Molecular brain research},
  volume={91 1-2},
This study used double in situ hybridization (ISH) to examine the colocalization of estrogen receptor beta (ERbeta) mRNA in serotonin neurons of rhesus macaques (Macaca mulatta). In addition, immunocytochemistry (ICC) was used to examine the expression and regulation of ERbeta protein in raphe neurons of the macaque midbrain. For double ISH, monkey specific riboprobes for ERbeta incorporating radiolabeled-UTP and a riboprobe for the human serotonin reuptake transporter (SERT) incorporating… CONTINUE READING
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