Estrogen receptor antagonism uncovers gender-dimorphic suppression of whole body fat oxidation in humans: differential effects of tamoxifen on the GH and gonadal axes.

@article{Birzniece2015EstrogenRA,
  title={Estrogen receptor antagonism uncovers gender-dimorphic suppression of whole body fat oxidation in humans: differential effects of tamoxifen on the GH and gonadal axes.},
  author={V. Birzniece and K. Ho},
  journal={European journal of endocrinology},
  year={2015},
  volume={173 4},
  pages={
          479-87
        }
}
CONTEXT Tamoxifen, a selective estrogen receptor modulator, suppresses GH secretion in women but not in men. It increases testosterone levels in men. As GH and testosterone stimulate fat metabolism, the metabolic consequences of tamoxifen may be greater in women than in men. OBJECTIVE To determine whether tamoxifen suppresses fat oxidation (Fox) to a greater degree in women than in men. DESIGN An open-label study of ten healthy postmenopausal women and ten healthy men receiving 2-week… Expand
Sex steroids and the GH axis: Implications for the management of hypopituitarism.
  • V. Birzniece, K. Ho
  • Medicine
  • Best practice & research. Clinical endocrinology & metabolism
  • 2017
Developing Modern Pain Therapies

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