Estrogen receptor alpha polymorphism and risk of cardiovascular disease, cancer, and hip fracture: cross-sectional, cohort, and case-control studies and a meta-analysis.

@article{Kjaergaard2007EstrogenRA,
  title={Estrogen receptor alpha polymorphism and risk of cardiovascular disease, cancer, and hip fracture: cross-sectional, cohort, and case-control studies and a meta-analysis.},
  author={Alisa D Kjaergaard and Christina Ellervik and Anne Tybjaerg-Hansen and Christen Kirk Axelsson and M L Gr\onholdt and P. Grande and Gorm Boje Jensen and B\orge G. Nordestgaard},
  journal={Circulation},
  year={2007},
  volume={115 7},
  pages={861-71}
}
BACKGROUND We hypothesized that the estrogen receptor alpha (ESR1) IVS1-397T/C polymorphism affects high-density lipoprotein cholesterol response to hormone replacement therapy and risk of cardiovascular disease (CVD), cancer of reproductive organs, and hip fracture. METHODS AND RESULTS We studied cross-sectionally 9244 individuals from the Danish general population and followed them up for 23 to 25 years. End points were CVD (ischemic heart disease, myocardial infarction, angina pectoris… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

Similar Papers

Loading similar papers…