Estrogen receptor αlpha gene (ESR1) PvuII and XbaI polymorphisms are associated to metabolic and proinflammatory factors in polycystic ovary syndrome.

@article{Silva2015EstrogenR,
  title={Estrogen receptor αlpha gene (ESR1) PvuII and XbaI polymorphisms are associated to metabolic and proinflammatory factors in polycystic ovary syndrome.},
  author={F S Silva and Mirelle Oliveira S{\'o}ter and Mariana F. Sales and Ana L{\'u}cia C{\^a}ndido and F M Reis and I{\^e}da de F{\'a}tima O Silva and Marinez de Oliveira Sousa and Cl{\'a}udia Nat{\'a}lia Ferreira and Karina B Gomes},
  journal={Gene},
  year={2015},
  volume={560 1},
  pages={44-9}
}
BACKGROUND Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that involves multiple factors. Although the etiology of PCOS is unknown, there is an involvement of sex steroid hormones in the pathophysiology of this syndrome. Therefore, polymorphisms in genes involved in the action of estrogen may contribute to a woman's susceptibility to PCOS… CONTINUE READING