Estrogen protects the liver and intestines against sepsis-induced injury in rats.

@article{ener2005EstrogenPT,
  title={Estrogen protects the liver and intestines against sepsis-induced injury in rats.},
  author={G{\"o}ksel Şener and Serap Arbak and Pelin Kurtaran and Nursal Gedik and Berrak Cağlayan Yeğen},
  journal={The Journal of surgical research},
  year={2005},
  volume={128 1},
  pages={70-8}
}
BACKGROUND AND AIM Sepsis is commonly associated with enhanced generation of reactive oxygen metabolites, leading to multiple organ dysfunctions. The aim of this study was to examine the putative protective role of estradiol against sepsis-induced oxidative organ damage. MATERIALS AND METHODS Sepsis was induced by cecal ligation and puncture method in Wistar albino rats. Sham-operated (control) and sepsis groups received saline or estradiol propionate (10 mg/kg) intraperitoneally immediately… CONTINUE READING

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