Estrogen plus progestin use, microsatellite instability, and the risk of colorectal cancer in women.

@article{Newcomb2007EstrogenPP,
  title={Estrogen plus progestin use, microsatellite instability, and the risk of colorectal cancer in women.},
  author={Polly A Newcomb and Yingye Zheng and Victoria M. Chia and Libby M Morimoto and Vincent Paul Doria-Rose and Allyson S. Templeton and Stephen N. Thibodeau and John D. Potter},
  journal={Cancer research},
  year={2007},
  volume={67 15},
  pages={7534-9}
}
Current users of postmenopausal hormones (PMH) have approximately 30% to 40% lower risk of colorectal cancer (CRC), although associations with specific types of hormones have been inconsistent. Further, it is not clear whether some tumor types have a different risk. We conducted a case-control study to examine the relationship between PMH and CRC. Cases (n = 1,004), ages 50 to 74 years, were identified from the Surveillance Epidemiology and End Results registry in Washington from 1998 to 2002… CONTINUE READING