Estrogen modulates oxytocin gene expression in regions of the rat supraoptic and paraventricular nuclei that contain estrogen receptor-beta.

@article{Shughrue2002EstrogenMO,
  title={Estrogen modulates oxytocin gene expression in regions of the rat supraoptic and paraventricular nuclei that contain estrogen receptor-beta.},
  author={Paul J. Shughrue and Tammy L. Dellovade and Istv{\'a}n J. Merchenthaler},
  journal={Progress in brain research},
  year={2002},
  volume={139},
  pages={15-29}
}
Oxytocin is an important modulator of female reproductive functions including parturition, lactation and maternal behavior, while vasopressin regulates water balance and acts as a neurotransmitter. For decades, it has been suggested that estrogen regulates the production and/or release of oxytocin and vasopressin in the rodent brain. Although several studies demonstrated that estrogen can modulate vasopressin mRNA levels in regions known to contain estrogen receptor (ER), such as the bed… CONTINUE READING

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