Estrogen metabolizing enzymes in endometrium and endometriosis.

@article{Dassen2007EstrogenME,
  title={Estrogen metabolizing enzymes in endometrium and endometriosis.},
  author={H H N M Dassen and Chamindie Punyadeera and Rick Kamps and Bert Delvoux and Anne van Langendonckt and Jacques Donnez and Bettina Husen and Hubert H. Thole and Gerard A. J. Dunselman and Patrick G Groothuis},
  journal={Human reproduction},
  year={2007},
  volume={22 12},
  pages={3148-58}
}
BACKGROUND Estradiol (E(2)) is an important promoter of the growth of both eutopic and ectopic endometrium. The findings with regard to the expression and activity of steroidogenic enzymes in endometrium of controls, in endometrium of endometriosis patients and in endometriotic lesions are not consistent. METHODS In this study, we have looked at the mRNA expression and protein levels of a range of steroidogenic enzymes [aromatase, 17beta-hydroxysteroid dehydrogenases (17beta-HSD) type 1, 2… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

Dienogest reduces HSD17β1 expression and activity in endometriosis.

The Journal of endocrinology • 2015
View 4 Excerpts
Highly Influenced

Activin A Stimulates Aromatase via the ALK4-Smad Pathway in Endometriosis

BioMed research international • 2016
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 68 references

Steroid sulfatase and estrogen sulfotransferase in human endometrial carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2004
View 3 Excerpts
Highly Influenced

Aromatase expression in endometriosis.

The Journal of clinical endocrinology and metabolism • 1996
View 7 Excerpts
Highly Influenced

A sensitive HPLC method for the assessment of metabolic conversion of estrogens.

The Journal of steroid biochemistry and molecular biology • 2007
View 1 Excerpt

Expression analysis of the genes involved in estradiol and progesterone action in human ovarian endometriosis.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2007
View 8 Excerpts

Similar Papers

Loading similar papers…