Estrogen-mediated impairment of macrophageal uptake of environmental TiO2 particles to explain inflammatory effect of TiO2 on airways during pregnancy

  title={Estrogen-mediated impairment of macrophageal uptake of environmental TiO2 particles to explain inflammatory effect of TiO2 on airways during pregnancy},
  author={Yiming Zhang and Lyudmila Mikhaylova and Lester Kobzik and Alexey V Fedulov},
  journal={Journal of Immunotoxicology},
  pages={81 - 91}
Abstract Innate defenses against environmental particulate exposures can become deficient when physiological background of the organism is unbalanced. Even those exposures considered innocuous may then become harmful. For example, one of the important inherent risks of pregnancy is increased inflammatory responsiveness in the airways, which extends to exposures considered otherwise innocuous: it has been observed that normally “inert” particulates become inflammatory in pregnancy. They lead to… 
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