Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element.

@article{Sabbah1999EstrogenIO,
  title={Estrogen induction of the cyclin D1 promoter: involvement of a cAMP response-like element.},
  author={Mich{\`e}le Sabbah and Delphine Courilleau and Jan Mester and G{\'e}rard Redeuilh},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 20},
  pages={11217-22}
}
Estrogens induce cell proliferation in target tissues by stimulating progression through the G(1) phase of the cell cycle. Induction of cyclin D1 expression is a critical feature of the mitogenic action of estrogen. We have determined a region between -96 and -29 in the cyclin D1 promoter that confers regulation by estrogens in the human mammary carcinoma cells MCF-7. This region encompasses a unique known transcription factor binding site with a sequence of a potential cAMP response element… CONTINUE READING
118 Citations
1 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 118 extracted citations

References

Publications referenced by this paper.

Sabbah et al

  • 97 NuclearReceptorsNomenclatureCommitteeCell, 161–163. 11222 Biochemistry
  • Proc. Natl. Acad. Sci. USA 96
  • 1999

Similar Papers

Loading similar papers…