Estrogen-induced remodeling of hypothalamic neural circuitry.

  title={Estrogen-induced remodeling of hypothalamic neural circuitry.},
  author={Loretta M. Flanagan-Cato},
  journal={Frontiers in neuroendocrinology},
  volume={21 4},
For decades, sexual behavior has been a valuable model system for behavioral neuroscientists studying the neural basis of motivated behaviors. One striking example of a change in motivation is the binary switch in sexual receptivity that occurs during the estrous cycle in female rats. Investigations of the neural basis of this change in behavior have fundamentally advanced our understanding of both behaviorally relevant neural pathways and basic mechanisms of steroid action in the brain. These… CONTINUE READING