Estrogen increases affinity of oxytocin receptors in the medial preoptic area-anterior hypothalamus.

@article{Caldwell1994EstrogenIA,
  title={Estrogen increases affinity of oxytocin receptors in the medial preoptic area-anterior hypothalamus.},
  author={Jack Daniel Caldwell and Cheryl H. Walker and Cort A. Pedersen and Azzam Barakat and George A. Mason},
  journal={Peptides},
  year={1994},
  volume={15 6},
  pages={1079-84}
}
Analysis of binding data from saturation experiments using a radiolabeled oxytocin antagonist ([125I]OTA) demonstrated an increase in binding affinity after treatment with 5 micrograms estradiol benzoate (EB) for 3 days in membrane fractions from the medial preoptic area-anterior hypothalamus (MPOA-AH) of ovariectomized (OVX) rats. Analysis of data from competition experiments revealed high- and low-affinity [125I]OTA binding sites in the MPOA-AH, the medial basal hypothalamus (MBH), and… CONTINUE READING

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Treatment of membrane fractions from the MPOA - AH of oil - treated OVX rats in vitro with 100 nM OT or with estrogen or progesterone conjugated to bovine serum albumin ( E - BSA and P - BSA ) also reduced low - affinity [ 125I]OTA binding sites but BSA alone did not .
Treatment of membrane fractions from the MPOA - AH of oil - treated OVX rats in vitro with 100 nM OT or with estrogen or progesterone conjugated to bovine serum albumin ( E - BSA and P - BSA ) also reduced low - affinity [ 125I]OTA binding sites but BSA alone did not .
Analysis of binding data from saturation experiments using a radiolabeled oxytocin antagonist ( [ 125I]OTA ) demonstrated an increase in binding affinity after treatment with 5 micrograms estradiol benzoate ( EB ) for 3 days in membrane fractions from the medial preoptic area - anterior hypothalamus ( MPOA - AH ) of ovariectomized ( OVX ) rats .
Estrogen increases affinity of oxytocin receptors in the medial preoptic area - anterior hypothalamus .
Analysis of binding data from saturation experiments using a radiolabeled oxytocin antagonist ( [ 125I]OTA ) demonstrated an increase in binding affinity after treatment with 5 micrograms estradiol benzoate ( EB ) for 3 days in membrane fractions from the medial preoptic area - anterior hypothalamus ( MPOA - AH ) of ovariectomized ( OVX ) rats .
Estrogen increases affinity of oxytocin receptors in the medial preoptic area - anterior hypothalamus .
Analysis of binding data from saturation experiments using a radiolabeled oxytocin antagonist ( [ 125I]OTA ) demonstrated an increase in binding affinity after treatment with 5 micrograms estradiol benzoate ( EB ) for 3 days in membrane fractions from the medial preoptic area - anterior hypothalamus ( MPOA - AH ) of ovariectomized ( OVX ) rats .
Estrogen increases affinity of oxytocin receptors in the medial preoptic area - anterior hypothalamus .
Analysis of binding data from saturation experiments using a radiolabeled oxytocin antagonist ( [ 125I]OTA ) demonstrated an increase in binding affinity after treatment with 5 micrograms estradiol benzoate ( EB ) for 3 days in membrane fractions from the medial preoptic area - anterior hypothalamus ( MPOA - AH ) of ovariectomized ( OVX ) rats .
Estrogen increases affinity of oxytocin receptors in the medial preoptic area - anterior hypothalamus .
Analysis of binding data from saturation experiments using a radiolabeled oxytocin antagonist ( [ 125I]OTA ) demonstrated an increase in binding affinity after treatment with 5 micrograms estradiol benzoate ( EB ) for 3 days in membrane fractions from the medial preoptic area - anterior hypothalamus ( MPOA - AH ) of ovariectomized ( OVX ) rats .
Estrogen increases affinity of oxytocin receptors in the medial preoptic area - anterior hypothalamus .
Treatment of membrane fractions from the MPOA - AH of oil - treated OVX rats in vitro with 100 nM OT or with estrogen or progesterone conjugated to bovine serum albumin ( E - BSA and P - BSA ) also reduced low - affinity [ 125I]OTA binding sites but BSA alone did not .
Treatment of membrane fractions from the MPOA - AH of oil - treated OVX rats in vitro with 100 nM OT or with estrogen or progesterone conjugated to bovine serum albumin ( E - BSA and P - BSA ) also reduced low - affinity [ 125I]OTA binding sites but BSA alone did not .
Treatment of membrane fractions from the MPOA - AH of oil - treated OVX rats in vitro with 100 nM OT or with estrogen or progesterone conjugated to bovine serum albumin ( E - BSA and P - BSA ) also reduced low - affinity [ 125I]OTA binding sites but BSA alone did not .
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