Estrogen in Patients with Prostatic Cancer
@article{Henriksson1991EstrogenIP, title={Estrogen in Patients with Prostatic Cancer}, author={Peter Henriksson}, journal={Drug Safety}, year={1991}, volume={6}, pages={47-53} }
SummaryEstrogen therapy of patients with prostatic carcinoma appears to be at least as effective in antitumour activity as surgical castration; the recent therapeutic alternative of gonadorelin (gonadotrophin-releasing hormone) analogues has not to date been shown to improve patient outcome.Oral estrogen therapy in these patients increases the incidence of arterial ischaemic events, thromboembolic events and congestive heart failure. A plausible mechanism behind the enhanced cardiovascular…
4 Citations
Leuprorelin. A review of its pharmacology and therapeutic use in prostatic disorders.
- Medicine, BiologyDrugs & aging
- 1991
Small noncomparative trials reveal that leuprorelin also causes regression of benign hyperplastic prostate tissue with corresponding relief of obstructive, but not irritative, symptoms although continuous treatment is necessary to maintain remission.
Increased Mean Platelet Volume after Oestrogen Replacement Therapy
- Medicine, BiologyAnnals of clinical biochemistry
- 1996
HRT appears to increase mean platelets volume which may indicate an increase in platelet reactivity, and there was no correlation between the changes in mean platelet volume and membrane fatty acid changes in platelets after such therapy.
Effects of ethinyl oestradiol/polyoestradiol phosphate and estramustine phosphate on some proteins related to haemostasis in prostatic carcinoma patients
- Medicine, BiologyInternational Urology and Nephrology
- 2006
It was found that both EE/EP and EM treatment induced significant decreases of orosomucoid, haptoglobin, antithrombin III and C1-inhibitor, while the same treatment increased the plasma concentration of alpha-1-antitrypsin.
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