Estrogen enhances wound healing in the penis of rats.

  title={Estrogen enhances wound healing in the penis of rats.},
  author={Chishimba Nathan Mowa and Renee Hoch and C L Montavon and Subrina Jesmin and Greg Hindman and Guo-sheng Hou},
  journal={Biomedical research},
  volume={29 5},
Estrogen receptor (ER) alpha and beta and aromatase are expressed in various cell-types and compartments of the penis, including the epidermis of glans penis. Here, we hypothesize that estrogen helps maintain the viability and integrity of glans penis and test the hypothesis by treating lesioned glans penis with either 17beta-estradiol or vehicle only. Estrogen was found to facilitate wound healing and increase vascular endothelial growth factor (VEGF) immunoreactivity compared to control, as… CONTINUE READING