Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression.

@article{Clarkson2018EstrogenEO,
  title={Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression.},
  author={Thomas B. Clarkson},
  journal={Menopause},
  year={2018},
  volume={25 11},
  pages={
          1262-1274
        }
}
The past several years have been marked by confusion and controversy concerning whether estrogens are cardioprotective. The issue is of utmost public health importance because coronary heart disease (CHD) remains the leading cause of death among postmenopausal women. Fortunately, a unifying hypothesis has emerged that reproductive stage is a major determinant of the effect of estrogens on atherosclerosis progression, complications, and plaque vulnerability. PREMENOPAUSAL YEARS Premenopausal… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 83 REFERENCES

Inflammation in atherosclerosis.

  • Arteriosclerosis, thrombosis, and vascular biology
  • 2012

Effects of conjugated equine estrogens in postmenopausal women with hysterectomy — the WHI randomized controlled trial

Salpter, Walsh JME, E Greyber, EE Salpeter
  • JAMA
  • 2004