Estrogen deficiency affects bone healing around titanium implants: a histometric study in rats.

@article{Duarte2003EstrogenDA,
  title={Estrogen deficiency affects bone healing around titanium implants: a histometric study in rats.},
  author={Poliana Mendes Duarte and Jo{\~a}o Batista C{\'e}sar Neto and P. F. C. Goncalves and En{\'i}lson Ant{\^o}nio Sallum and J F Nociti},
  journal={Implant dentistry},
  year={2003},
  volume={12 4},
  pages={340-6}
}
The purpose of this study was to evaluate the influence of an estrogen-deficient state on bone around titanium implants placed in rats. Thirty female Wistar rats were divided into 2 groups: test (n = 15), ovariectomized rats (OVX); and control (n = 15), sham-operated rats. Screw-type titanium implants were placed bilaterally in rats 21 days after ovariectomy or sham surgery. After 60 days, the animals were killed and undecalcified sections obtained. Blood samples were collected to obtain serum… CONTINUE READING

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