Estrogen as an immunomodulator.

  title={Estrogen as an immunomodulator.},
  author={Thomas J. Lang},
  journal={Clinical immunology},
  volume={113 3},
Estrogen's role in the sex differences observed in autoimmune diseases such as systemic lupus, multiple sclerosis, and rheumatoid arthritis have remained unclear. Complicating the understanding of the immunomodulatory effects of estrogen are (1) the effects of estrogen on multiple components of the immune response; (2) its varied effects on different systems in which it appears pro-autoimmune, as in murine lupus, or anti-inflammatory, as in EAE; and (3) its effects on other hormones which are… CONTINUE READING


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