Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases.

@article{Vegeto2008EstrogenAA,
  title={Estrogen anti-inflammatory activity in brain: a therapeutic opportunity for menopause and neurodegenerative diseases.},
  author={Elisabetta Vegeto and Valeria Benedusi and Adriana C Maggi},
  journal={Frontiers in neuroendocrinology},
  year={2008},
  volume={29 4},
  pages={507-19}
}
Recent studies highlight the prominent role played by estrogens in protecting the central nervous system (CNS) against the noxious consequences of a chronic inflammatory reaction. The neurodegenerative process of several CNS diseases, including Multiple Sclerosis, Alzheimer's and Parkinson's Diseases, is associated with the activation of microglia cells, which drive the resident inflammatory response. Chronically stimulated during neurodegeneration, microglia cells are thought to provide… CONTINUE READING
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