Estrogen- and tamoxifen-associated effects on brain structure and function

  title={Estrogen- and tamoxifen-associated effects on brain structure and function},
  author={J. Eberling and C. Wu and Regina Tong-Turnbeaugh and W. Jagust},
  • J. Eberling, C. Wu, +1 author W. Jagust
  • Published 2004
  • Psychology, Medicine, Computer Science
  • NeuroImage
  • We evaluated the effects of estrogen and tamoxifen, a selective estrogen receptor modulator, on positron emission tomography (PET) measures of brain glucose metabolism and magnetic resonance imaging (MRI) measures of hippocampal atrophy. Three groups of postmenopausal women were studied, women taking estrogen (ERT+), women with breast cancer taking tamoxifen (TAM), and women not taking estrogen or tamoxifen (ERT-). All subjects received a PET scan, an MRI scan, and cognitive testing. The TAM… CONTINUE READING
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