Estrogen and progesterone receptor assay in paraffin-embedded breast cancer--reproducibility of assessment.

@article{Chebil2003EstrogenAP,
  title={Estrogen and progesterone receptor assay in paraffin-embedded breast cancer--reproducibility of assessment.},
  author={Gunilla Chebil and P{\"a}r-Ola Bendahl and M{\aa}rten Fern{\"o}},
  journal={Acta oncologica},
  year={2003},
  volume={42 1},
  pages={43-7}
}
Immunohistochemical (IHC) assays are routinely used for determining the estrogen receptor (ER) and progesterone receptor (PgR) status of women with breast cancer. The present knowledge of reproducibility of the subjective IHC assessment is limited. The purpose of this study was to evaluate the interobserver reproducibility in IHC assessment of 127 (ER) and 126 (PgR) cases of primary breast cancer. The slides were independently re-assessed by 22 pathologists from nine hospitals. A simple… CONTINUE READING

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