Estrogen alters remodeling of the vaginal wall after surgical injury in guinea pigs.


Loss of pelvic organ support (i.e., pelvic organ prolapse) is common in menopausal women. Surgical reconstruction of pelvic organ prolapse is plagued with high failure rates. The objective of this study was to determine the effects of estrogen on biomechanical properties, lysyl oxidase (LOX), collagen content, and histomorphology of the vagina with or… (More)
DOI: 10.1095/biolreprod.113.112367

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