Estrogen action in mood and neurodegenerative disorders

@article{sterlund2007EstrogenAI,
  title={Estrogen action in mood and neurodegenerative disorders},
  author={M. {\"O}sterlund and M. Witt and J. Gustafsson},
  journal={Endocrine},
  year={2007},
  volume={28},
  pages={235-241}
}
  • M. Österlund, M. Witt, J. Gustafsson
  • Published 2007
  • Medicine
  • Endocrine
    • In this review, estrogenic effects in depression, anxiety, and neurodegenerative disorders are summarized. Moreover, preclinical findings from in vitro and animal models are discussed. There is a correlation between decreased estrogen levels (e.g., premenstrually, during the postpartum period, and perimenopausally) and increased anxiety and depressive symptoms. Several studies show beneficial effects of estrogen treatment in women with anxiety and depressive symptoms. Recent data indicate that… CONTINUE READING
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    References

    SHOWING 1-10 OF 125 REFERENCES
    The role of estrogen in mood disorders in women
    • J. Payne
    • Psychology, Medicine
    • International review of psychiatry
    • 2003
    • 116
    Role of Estrogen in the Treatment of Depression
    • 62
    Increased anxiety and synaptic plasticity in estrogen receptor β-deficient mice
    • 222
    • PDF
    Gonadal steroids in the treatment of mood disorders.
    • 122
    Estrogen control of central neurotransmission: Effect on mood, mental state, and memory
    • 297
    The role of estrogen in schizophrenia.
    • M. Seeman
    • Psychology, Medicine
    • Journal of psychiatry & neuroscience : JPN
    • 1996
    • 124
    Neurotrophic and neuroprotective actions of estrogens and their therapeutic implications.
    • 482
    Estrogen receptor-α mediates the brain antiinflammatory activity of estradiol
    • 315
    • PDF
    Are estrogens protective or risk factors in brain injury and neurodegeneration? Reevaluation after the Women's health initiative.
    • 145
    • PDF
    Alzheimer’s disease: the impact of age-related changes in reproductive hormones
    • 64