Estrogen action in mood and neurodegenerative disorders

  title={Estrogen action in mood and neurodegenerative disorders},
  author={M. {\"O}sterlund and M. Witt and J. Gustafsson},
  • M. Österlund, M. Witt, J. Gustafsson
  • Published 2007
  • Medicine
  • Endocrine
  • In this review, estrogenic effects in depression, anxiety, and neurodegenerative disorders are summarized. Moreover, preclinical findings from in vitro and animal models are discussed. There is a correlation between decreased estrogen levels (e.g., premenstrually, during the postpartum period, and perimenopausally) and increased anxiety and depressive symptoms. Several studies show beneficial effects of estrogen treatment in women with anxiety and depressive symptoms. Recent data indicate that… CONTINUE READING
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