Estrogen Modulates the Recruitment of Myelopoietic Cell Progenitors in Rat Through a Stromal Cell-Independent Mechanism Involving Apoptosis


Loss of ovarian function leads t o a significant increase in the number of bone-resorbing osteoclasts. Estrogen replacement is known t o manifest bone protective effects in the treatment of postmenopausal osteoporosis. In the present study, we used ovariectomized rats t o examine the effects of estrogen loss at the osteoclast progenitor colony forming unit… (More)


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