Estrogen-Based Hormone Therapy for Depression Related to Reproductive Events

@article{Myoraku2018EstrogenBasedHT,
  title={Estrogen-Based Hormone Therapy for Depression Related to Reproductive Events},
  author={Alison Myoraku and Thalia K. Robakis and Natalie L. Rasgon},
  journal={Current Treatment Options in Psychiatry},
  year={2018},
  volume={5},
  pages={416-424}
}
PurposeIn this review, we provide an overview of recent literature on the use of estrogen-based hormone therapy to treat depression related to reproductive events, like postpartum and perimenopause. Women are two to four times more likely to become depressed in the perimenopausal stage of life and as many as 14.5% of women develop postpartum depression. It is hypothesized that these depressive symptoms are a result of fluctuations in hormone levels during these windows of vulnerability. To… 

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