Estrogen‐related Mood Disorders: Reproductive Life Cycle Factors

@article{Douma2005EstrogenrelatedMD,
  title={Estrogen‐related Mood Disorders: Reproductive Life Cycle Factors},
  author={S L Douma and Charles H. Husband and Mary Ellen O'Donnell and B. N. Barwin and A. Kirsten Woodend},
  journal={Advances in Nursing Science},
  year={2005},
  volume={28},
  pages={364–375}
}
Women are at higher risk throughout their reproductive lives than are men for major depression. Numerous molecular and clinical studies have implicated estrogen in modulating brain function including that related to mood. In an attempt to present a conceptual model, the literature of the past 30 years on mood and well-being throughout reproductive life is reviewed as it relates to activity of endogenous, bio-identical, and synthetic estrogen in women. Results indicate that sudden estrogen… 

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