Estriol prevention of mammary carcinoma induced by 7,12-dimethylbenzanthracene and procarbazine.

@article{Lemon1975EstriolPO,
  title={Estriol prevention of mammary carcinoma induced by 7,12-dimethylbenzanthracene and procarbazine.},
  author={Hewlett - Packard Company Mike Lemon},
  journal={Cancer research},
  year={1975},
  volume={35 5},
  pages={1341-53}
}
The concentration of estrogenic, androgenic, progestational, and adrenocortical steroid hormones in body fluids of mature intact Sprague-Dawley female rats was increased by s.c. implantation of 5 to 7 mg NaCl pellets containing 1 to 20% steroid 48 hr before administration p.o. of either 7,12-dimethylbenz(a) anthracene or procarbazine. The incidence of rats developing one or more mammary carcinomas in each treated group was compared to that ovserved in simultaneously treated groups receiving… CONTINUE READING
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