Estramustine phosphate compared with diethylstilbestrol. A randomized, double-blind, crossover trial for stage D prostate cancer.

@article{Benson1986EstramustinePC,
  title={Estramustine phosphate compared with diethylstilbestrol. A randomized, double-blind, crossover trial for stage D prostate cancer.},
  author={Ralph C. Benson and Gurinder Gill},
  journal={American journal of clinical oncology},
  year={1986},
  volume={9 4},
  pages={341-51}
}
In a double-blind, crossover comparison, 236 patients with metastatic prostate cancer were randomized to receive estramustine phosphate (EMP) or diethylstilbestrol (DES). Previously castrated patients (66) were separately randomized. Patients kept taking their first drug until progression was proved by objective studies, at which time alternative treatment… CONTINUE READING