Estradiol protects against ischemic brain injury in middle-aged rats.

@article{Wise2000EstradiolPA,
  title={Estradiol protects against ischemic brain injury in middle-aged rats.},
  author={Phyllis M. Wise and Dena B. Dubal},
  journal={Biology of reproduction},
  year={2000},
  volume={63 4},
  pages={982-5}
}
Several clinical studies suggest that estradiol acts as a potent growth and protective factor in the adult brain. Postmenopausal women experience permanent hypoestrogenicity and suffer from increased risk of brain injury associated with neurodegenerative diseases such as stroke and Alzheimer's disease. Estrogen replacement therapy appears to decrease the risk and severity of these neurodegenerative conditions. Studies using animal models have shown that estradiol exerts similar effects in… CONTINUE READING

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Postmenopausal women experience permanent hypoestrogenicity and suffer from increased risk of brain injury associated with neurodegenerative diseases such as stroke and Alzheimer 's disease .
Postmenopausal women experience permanent hypoestrogenicity and suffer from increased risk of brain injury associated with neurodegenerative diseases such as stroke and Alzheimer 's disease .
Postmenopausal women experience permanent hypoestrogenicity and suffer from increased risk of brain injury associated with neurodegenerative diseases such as stroke and Alzheimer 's disease .
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