Estradiol phase-shifts circannual rhythms of golden-mantled ground squirrels.

  title={Estradiol phase-shifts circannual rhythms of golden-mantled ground squirrels.},
  author={T M Lee and Irving Zucker},
  journal={The American journal of physiology},
  volume={262 6 Pt 2},
Ovariectomized golden-mantled ground squirrels (Spermophilus lateralis) were implanted with estradiol benzoate (EB)-filled or empty capsules. Body weight was monitored for at least 1 yr before, during, and after hormone treatment. EB treatment of 6-7 mo duration, restricted to the weight-gain phase, decelerated weight gain and delayed attainment of peak weight by 34 days; the period of the circannual rhythm, measured between successive trough weights, was 36 days longer in squirrels treated… CONTINUE READING

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