Estradiol-induced mitotic delay in HeLa cells: reversal by calcium chloride and putrescine.
@article{Rao1969EstradiolinducedMD, title={Estradiol-induced mitotic delay in HeLa cells: reversal by calcium chloride and putrescine.}, author={Potu N. Rao}, journal={Experimental cell research}, year={1969}, volume={57 2}, pages={ 230-4 } }
18 Citations
Mitotic inhibition and chromosome displacement induced by estradiol in Chinese hamster cells.
- BiologyCell motility and the cytoskeleton
- 1987
Microtubule experiments showed that DES inhibited spindleAssembly and disassembled the CMTC, whereas estradiol, at similar concentrations, arrested mitosis in a manner that allowed spindle assembly, and changes in cell morphology were observed.
An estradiol mitotic rate inhibiting effect in the Müllerian epithelium in neonatal mice.
- Biology, MedicineThe Journal of experimental zoology
- 1970
At a continued treatment with estradiol, the mitotic rate values decreased to a level somewhat below the control level in the uterine horns; in the uterus cervix and mullerian vagina theMitotic rate decreased to very low values, significantly lower than in the corresponding regions in the controls.
Mitotic inhibition and aneuploidy induction by naturally occurring and synthetic estrogens in Chinese hamster cells in vitro.
- BiologyMutation research
- 1986
Proliferative inhibition of human breast carcinoma cells by high concentration estradiol does not alter radiosensitivity
- Biology, MedicineBreast Cancer Research and Treatment
- 2005
SummaryThe proliferation of ER+ malignant mammary epithelial cells (MMEC), MCF-7 and T-47D, was markedly inhibited by 10µM 17β-estradiol (E2), while the ER− line, MDA-MB-231, was minimally affected.…
Accumulation of polyploid cells and G2‐phase cells during ascites tumor growth
- BiologyJournal of cellular physiology
- 1977
These studies indicate that the accumulation of 4C cells during the plateau phase of growth is due to a combination of G2 diploid and G1 tetraploid cells.
THE EFFECT OF ESTRADIOL ON THE CELL KINETICS IN THE UTERINE AND CERVICAL EPITHELIUM OF NEONATAL MICE
- Biology, MedicineCell and tissue kinetics
- 1975
The effect of estradiol‐17β on the length of the various phases of the cell cycle was studied in the neonatal mouse uterine, and cervical epithelium. A double labelling method was used, and in…
Radiation-induced division delay in synchronized Chinese hamster ovary cells in monolayer culture.
- BiologyRadiation research
- 1972
Chinese hamster ovary cells in monolayer culture, synchronized by mechanically selecting mitotic cells in the absence of drugs, were x-irradiated with 150, 300, or 600 rads at frequent intervals du...
Cytoplasmic and nuclear growth during the proliferation of Ehrlich ascites tumour cells in mice
- BiologyVirchows Archiv. B, Cell pathology
- 1972
There was a continuous enlargement of the average cell size and a consequential change in the cell size distribution and a simultaneous increase in the mean DNA content indicated an accumulation of cells in the postsynthetic period.
Effects of pharmacological concentrations of estrogens on proliferation and cell cycle kinetics of human breast cancer cell lines in vitro.
- Biology, MedicineCancer research
- 1987
The cell cycle changes associated with estrogen-induced growth inhibition in vitro are identical to those observed during regression of ER positive but not ER negative human tumor xenografts in nude mice.
Antigenotoxic effect of allicin against estradiol-17β-induced genotoxic damage in cultured mammalian cells
- BiologyNatural product research
- 2010
Antigenotoxic activity of allicin, one of the sulphur compounds of garlic (Allium sativum) which possesses antioxidant and thiol disulphide exchange activity, was studied against…
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