Estradiol: a protective factor in the adult brain.

@article{Wise2000EstradiolAP,
  title={Estradiol: a protective factor in the adult brain.},
  author={Phyllis M. Wise},
  journal={Journal of pediatric endocrinology & metabolism : JPEM},
  year={2000},
  volume={13 Suppl 6},
  pages={
          1425-9
        }
}
Clinical studies suggest that estradiol acts as a protective factor in the adult brain. Postmenopausal women suffer from an increased risk of brain injury associated with neurodegenerative diseases such as Alzheimer's disease, and estrogen replacement therapy appears to decrease the risk and severity of this neurodegenerative condition. Studies using animal models show that estradiol exerts similar effects in rodents and can enhance cell survival. Therefore, we designed experiments to determine… CONTINUE READING

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