Estimation of treatment preference effects in clinical trials when some participants are indifferent to treatment choice


BACKGROUND In the two-stage randomised trial design, a randomly sampled subset of study participants are permitted to choose their own treatment, while the remaining participants are randomised to treatment in the usual way. Appropriate analysis of the data from both arms of the study allows investigators to estimate the impact on study outcomes of… (More)
DOI: 10.1186/s12874-017-0304-x

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